Cannabis Science

2 December 2018

6 Facts about CBD you may not know

6 facts that you may not know about cannabidiol

By Mell Green

As the cannabis industry continues to grow, there’s one element that the world still gets consistently misinformed about: CBD (cannabidiol). When discussing anything related to cannabis, people often immediately think of THC (tetrahydrocannabinol). However, there’s certainly far more to it than this psychoactive component, which we’ve seen with the emergence of a flourishing CBD industry. CBD is nothing new; it’s only one of the latest and greatest cannabis discoveries, but with so much mixed information, many have been left in the dark about what it is and what it isn’t. But hold tight, because we have your back. Below, we share 6 facts that you may not know about cannabidiol.

Fact #1: CBD doesn’t directly stimulate CB1 and CB2 receptors.

The endocannabinoid system (ECS) is what essentially regulates the effects of cannabis in our bodies. In contrast to THC, CBD is non-intoxicating and doesn’t actually interact with receptors CB1 and CB2 found in this system. Instead, it works by indirectly acting as an antagonist and can block out certain chemicals and their effects in the body, for example THC, which causes a high. When consumed, it influences these two classical receptors by signaling the body’s naturally-produced cannabinoids (like anandamide) to increase by inhibiting enzymes that break them down.

Fact #2: CBD use is safe for pets.

Preliminary research has shown that  CBD seems to be beneficial and safe for all mammals. With the discovery of the endocannabinoid system, it turns out that all mammals share this  system and can experience CBD in much the same way humans do. This is due to cannabidiol’s lack of side effects, so now even pets can receive the wonderful benefits with this type of treatment, without inducing a high. CBD can promote youthfulness and vitality and many pet owners have bought CBD for animals suffering from a range of symptoms including joint pain, nausea, inflammation, anxiety, and more. It’s important to note that pets have more cannabinoid receptors than any other animal, so this makes treating them a very interesting proposition. In regards to THC, however, cats and dogs may experience a higher level of intensity compared to humans, so pet owners  should administer products containing THC with caution and consult with their veterinarian for a comprehensive review of their pet’s health and needs.

Fact #3: CBD interacts with other medications.

An enzyme found in the body called cytochrome P450 is involved in metabolizing many drugs and can be inhibited by CBD consumption. By doing so, CBD can either reduce or increase the effects of other drugs. If you are taking medication, make sure you consult with your health professional before adding cannabidiol to your treatment regimen.

Fact #4: CBD extraction method matters.

The quality of a CBD product depends on the extraction method used. For example, extracting CBD using a THC separation and purification heat-based process (decarboxylation) will have lost the majority of its health benefits. Another method is CBD crystallization, which CBD crystals are formed during the process of CBD isolation. With a little encouragement, in this process CBD molecules are forced out of the solution and reform into a substance with nearly 99% CBD purity and free of impurities. However, CBD extracted using carbon dioxide (CO2) allows for an individualized method and product, because temperatures and pressures can easily be changed at varying levels to separate CBD from THC. This method is deemed to be better than other extraction processes because it maintains the integrity of the end product by preserving all phytocannabinoids and synergistic compounds, free of solvents and other harsh chemicals.

Fact #5: CBD dosage varies for each person.

Finding the perfect dose for CBD isn’t easy and that’s because technically, there isn’t any. But, there’s no need to stress because the struggle to dose appropriately is quite common. Although every brand seems to offer different recommendations, everyone metabolizes CBD differently. There aren’t any confirmed CBD overdose cases, so the perhaps the best way to find your proper dosage is through your own personal exploration by starting low and increasing slowly over time or consulting your health professional.

Fact #6: CBD can undo the effects of THC.

Cannabinoids, terpenes, and other compounds found in cannabis interact with each other, and this is especially true in the complex relationship of CBD and THC. Although THC can have its own beneficial effects, it can also produce unwanted side effects, especially in large doses. Luckily, users can smooth out their high by balancing it with CBD. Consuming CBD after blazing up counters intense highs and effects produced by THC. Many of these side effects include nausea, increased pain sensation, anxiety, and paranoia.


It’s no doubt that CBD has a vast variety of unique medicinal benefits and as research grows in scientific and medical fields, more could potentially be discovered. If you’re interested in trying CBD products or maybe grow your own CBD strains, check out our shop

Post author
Mell Green
Mell Green is an enthusiast of all things cannabis and writes content that represents some of the best things that we as a people can strive for: good health and happiness.
See more from Mell Green

Leave a comment

You must be logged in to post a comment.

More articles you would like