Cannabis can help to reduce the symptoms of Attention Deficit Hyperactivity Disorder (ADHD) through two of its main cannabinoids; THC and CBD and the terpene α-Pinene. Preliminary studies have observed a connection between these compounds and a reduction of symptoms associated with ADHD such as; hyperactivity, impulsivity, lack of focus and learning difficulties. Even though not yet fully understood, it seems an 1:1 ratio of THC:CBD has a positive effect on emotional stability, memory, focus, learning ability and stress. This is possibly due to the interaction of these cannabinoids on the CB-1 receptor of the Endocannabinoid System (ECS) in adult human brains, which in turn, regulates the Dopamine (DA), Serotonin (5-HT), Mu- and Delta-opioid receptors, who are all involved with the negative symptoms of ADHD. The terpene Pinene seems to positively influence memory and helping the effectiveness of THC and CBD through the Entourage Effect.