Cannabis can help with depression through a number of cannabinoids and terpenes that work together through the Entourage Effect. One of the main ways cannabis combats depression is due to the positive effect CBD has on the production of serotonin by acting on the 5HT1A receptors in the brain. This effect is amplified by terpenes such as limonene and caryophyllene. 

THC, on its own, acts on the CB1/CB2 receptors, creating a buffer against depression due to its psychoactive effect (in low to medium doses). Together, THC and CBD can alleviate the major symptoms of depression like; insomnia, fatigue, loss of appetite and chronic pain.

According to the World Health Organisation (WHO more than 300 million people across the world experience depression. If you’re experiencing anxiety, low self-esteem, chronic stress and or a lack of appetite and sleep, there is a distinct possibility that you could be one of those millions who is currently fighting depression.

But have you considered the possibility that medical marijuana could actually be used to treat depression?

The common symptoms of depression include continuous low mood or sadness, feeling hopeless and helpless, having low self-esteem and or feelings of anxiety. While pharmaceutical drugs remain the most common treatments for depression, many more people are now considering several alternatives like medical cannabis. 

Indeed, in recent years, a growing body of scientific research has come to light, indicating strongly that medical marijuana has serious potential in helping to reduce the symptoms related to depression.

 

Research Highlights the Efficacy of Cannabis as a Treatment for Depression

The fascinating world of cannabis health continues to arouse the curiosity of scientists around the globe. As such, it was only natural for them to study the potential effects and medical benefits that medical cannabis could have when used as a treatment for the depression crisis that seems to be engulfing so much of our planet.

In September of 2019, a study published in the Journal of Affective Disorders, suggested that inhaling cannabis can significantly reduce short-term levels of depression. Of those taking part in the analysis, 89.3% experienced a significant reduction in feelings of depression. 

The analysis also revealed that cannabis was effective in reducing anxiety (over the short-term) and stress. Another study conducted in 2014 was carried out to understand the effects of CBD, one of the dominant cannabinoids in the cannabis plant. The analysis revealed that CBD interacted with the serotonin receptors in our brain, which, in turn, helped to lower anxiety and depression levels. 

As the level of research on cannabis increases, It is now thought that it could potentially help with depression relief through a number of cannabinoids and terpenes contained within the plant that synergise through the Entourage Effect. 

 

The Best Marijuana Strains for Depression 

There are many strains that may help in curbing depression symptoms due to the chemical balance of cannabinoids and cannabis terpenes displayed in the cannabis plant. 

With research and user testimony indicating that medical marijuana has the potential to treat depression, many people have started using different marijuana strains as an alternative treatment for the condition. For beginners, it can be a bit daunting trying to understand the differences between indica strains, sativa strains and CBD strains. 

Indeed, understanding the type of cannabis strains best suited to your needs is vital when using medical marijuana so, to help you on your way, we have compiled a list of some of the best strains for treating depression.

Pineapple Express

An increasingly popular choice and one of the best strains for treating depression is the world-famous hybrid Pineapple Express. This wonderfully uplifting strain boasts the combination of effectiveness and flavour or its parents, Trainwreck and Hawaiian.

The heavy-hitting combination of Trainwreck and Hawaiian produces a wonderful sativadominant hybrid with a THC ratio somewhere between 17-20% with low CBD readings of less than 1%.

With a terpene profile that contains caryophyllene, limonene and myrcene, this hugely popular cannabis cup winner can help to energize the body, and improve productivity, making it an excellent strain to treat depression.

Blue Dream

A sativadominant hybrid, with high levels of THC, Blue Dream is thought to be one of the best strains for relaxing both mind and body which also makes it one of the best cannabis strains for depression. 

With a high THC ratio (approaching 20%) Blue Dream is one of the more potent strains and thought to be particularly effective in the treatment of stress and depression. Blue Dream ́s terpene profile shows high levels of limonene, pinene, and myrcene that may help to control mood disorders.

A cross of Blueberry with Haze, Blue Dream is a sativa strain that achieves full-body relaxation with some subtle cerebral stimulation. With a sweet berry aroma similar to that of its Blueberry parent, Blue Dream can help to treat depression without any heavy sedative effects. As such, Blue Dream is a popular daytime medicine for those looking for a little depression relief. 

Sour Diesel

Commonly known as Sour D, this fantastic hybrid strain has the potential to aid several stress disorders, including physical pain, and, depression and anxiety.

Another sativa strain, this time a  sativadominant hybrid that is said to have descended from Chemdog 91 and Super Skunk, Sour Diesel is rich in terpenes caryophyllene, myrcene, and limonene that lend itself to this strains peppery, citrus-like aroma and taste. This fast-acting behemoth can produce energising cerebral effects that have made Sour Diesel a legendary strain amongst cannabis enthusiasts and medical patients looking to treat mood disorders.

With a high THC ratio between 16 and 20%,  Sour Diesel has the potential to lift your mood and energy levels, making it a great cannabis strain that could provide a strong antidepressant effect for those suffering from depression. 

Jack Herer

A descendant of Shiva Skunk and Northern Lights #5. Jack Herer is a wildly popular hybrid strain that is famed for its uplifting qualities and antidepressant effect that is said to induce both happiness and creativity.

This type of strain, a sativadominant hybrid, is favoured by many for their stress-relieving effects as well as their balanced blend of sativa and indica effects.

Jack Herer’s THC ratio usually sits around 15 to 20%, with its dominant terpenes terpinolene, limonene and pinene thought to be particularly useful in boosting mood and focus. With a rich, piney, woody aroma, Jack Herer is a smooth yet potent strain and amongst seasoned marijuana users, remains one of the best strains for treating depression and reducing anxiety. 

Other strains worthy of a mention include OG Kush, Super Silver Haze and any of the classic Cookies strains which can all prove to be potentially effective in reducing the symptoms of depression and anxiety.

Indeed, the potential benefits of cannabis on the mind and body seem to be endless so If you ́re one of the millions suffering from depression and you’re interested in growing your own cannabis to help treat depression, please visit our growing community for more information on our huge selection of award-winning and popular strains for depression relief.

We have a vast range of seeds including sativa and indica strains, CBD strains, CBD oils and much more to choose from including popular strains like Mango Kush, Girl Scout Cookies and Northern lights.

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    ACDC

    • Seeds

    Feminized

    ACDC is the sativa-dominant phenotype of the CBD-heavy Cannatonic, a strain with minimal psychoactive qualities. Although the strain has a 1:20 ratio of THC:CBD, its effects are surprisingly not followed by intense couch-lock. However, it is a difficult plant to grow, as it requires constant attention.

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    Stress Killer CBD

    • Juanita Lagrimosa
    • Lemon Haze

    Autoflowering

    Juanita Lagrimosa x Lemon Haze x Ruderalis (60/30/10) this sweet, lemony, CBD rich autoflowering hybrid, from Royal Queen Seeds, is a carefree delight for both recreational and medicinal consumers alike. 11% THC, with almost 1:1 CBD.

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    Royal Medic

    • Critical
    • Juanita Lagrimosa

    Feminized

    A magical combination of CBD-rich Juanita Lagrimosa and high-yielding Critical, Royal Medic is one of Royal Seeds special 1:1 medical varieties. With a balanced cannabinoid profile (10% THC/10% CBD ) and gorgeous fruity, hazey flavor.

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    Raspberry Waffles CBD

    • Strawberry Sour Diesel

    Regular

    A fruity, relatively high CBD strain from Devil´s Harvest Seeds, Raspberry Waffles CBD is a delicious cross of Strawberry Sour Diesel x a secret high CBD male. Remarkable for both its fabulous flavor and great medical potential. Upwards of 1% CBD.

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    Painkiller XL CBD

    • Royal Highness CBD

    Feminized

    Under the specialist hands of Royal Queen Seeds, the combination of Juanita La Lagrimosa x Royal Highness gives you the powerful medicinal strain, Painkiller XL CBD. A 75/25 sativa-dominant with a 1:1 CBD to THC ratio of approximately 9%. 

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    Medical Mass CBD

    • Critical

    Feminized

    Critical x Medical Madre gave Royal Queen Seeds this majestic, mainly indica strain (60%). She is popular with medical users who also seek some THC to help combat pain as she has an average of 10% THC and a 1:1 CBD ratio, which if anything falls heavier on the CBD side with an average of 11% CBD. She does well indoors and outdoors and is an easy grow.

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    Dinamed CBD

    • Seeds

    Feminized

    Dinafem brand their CBD-enriched Dinamed CBD as ‘the strain that won’t get you high’. The offspring of two Pure CBD #4 plants, it has as little as 0.5% THC and up to 14% CBD. A stable and heavy yielding hybrid with therapeutic effects.

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    Early Amnesia CBD

    • Original Amnesia

    Feminized

    A tasty, uber-enriched CBD strain from Dinafem. Early Amnesia CBD has a near 1:1 CBD to THC ratio, giving great medical effects and very light psychoactive ones. A delicious strain too, thanks to its strong sativa genes.

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    Swiss Cheese

    • Skunk #1

    Nirvana Seeds revived their well-known Swiss Miss strain by crossing her genetics with Skunk#1 to create this cheesy, pungent indica. Swiss Cheese has medium THC levels and high CBD levels. Her taste is funky and flavorful, and her aroma will undoubtedly attract some attention. Swiss Cheese is perfect for an evening dinner party with good friends as she promotes lively debate.

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    CBD Skunk Haze

    • Haze 1
    • Skunk #1

    Feminized | Medicinal

    Containing equal levels of CBD and THC, CBD Skunk Haze is a clear dedication to the medical marijuana community and one of the most sought-after cannabis hybrids that’s far more than its incredible parent strains. Heritage & Genetics: CBD Skunk Haze comes with crossing two legendary strains – Skunk #1…

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    Jorge’s Diamonds #1

    • Seeds

    Feminized

    Specially selected genetics from the famous Dutch Passion Research Gene Bank were selected by renowned cannabis guru, Jorges Cervantes, to create Jorge’s Diamonds #1. This sweet and potent strain produces bud as sparkly as the name suggests: a real jewel in this breeder´s crown.

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    Fast Eddy CBD

    • Juanita Lagrimosa
    • Ruderalis
    • UK Cheese

    Autoflowering

    Thanks to Royal Queen Seeds, the benefits of CBD strains like Fast Eddy are accessible to all. Light in its effect, broad in its medicinal applications and quick and easy-to-grow – everybody wins.

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    CBD Charlotte’s Angel

    • Dutch Charlotte
    • Red Angel

    Autoflowering, Feminized | Medicinal

    A remarkable medicinal strain, Charlotte’s Angel from Dutch Passion is an 80/20  sativa-dominant hybrid that is non-psychoactive. She provides all the flavor of strong THC varieties but without the high. Yet, you will still feel the distinctive mellowing effects of the crazily high concentration of CBD (15%). Heritage & Genetics:…

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    Dance World CBD

    • Dance Hall
    • Juanita Lagrimosa

    Feminized

    Dance World CBD by Royal Queen Seeds is a 75% sativa hybrid with strong indica traits. This is a strain with great medical properties, attributable to the very high CBD content and equally balanced THC levels. The overall effect is a mix of physical and mental sensation of total wellbeing.

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    Euphoria CBD

    • Royal Medic
    • Shark Shock

    Feminized

    Euphoria CDB is an 80% indica hybrid that’s rewarding to both grow and consume, and although low in THC, its high CBD content (almost 1:1) compensates for loss of psychoactivity.

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To ensure this, we use plain 20x27 white bubble wrap envelopes without any visible labelling except for your adres and our return address.
Our company name will read as “Guru Trading BV”. No other company labels, receipts or any references to cannabis are included on the envelope.

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What our users say

This website was recommended to me, it was exactly what I was looking for. So much useful information, I could literally read for hours. This is now where I get my CBD oil and my purple punch seeds are growing nicely. They also have really unique and useful packaging for the seeds. Cool company!
siun mcfaden
siun mcfaden
19:01 19 Jun 19
Personalized customer service and updates to the status of the order. I would very much recommend Coffeeshop Guru. In addition, they carry specialized seeds for less that other shops. I am a very happy client.
April Fregd
April Fregd
11:30 06 Jul 19
Informative website. Products are delivered with care. I am very satisfied with my new Amnesia Haze seeds. Let them grow, Guru go go go!
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Pieter Van Vliet
14:50 24 Jun 19
I'm impressed with the website and the variety of products they stock. My order arrived in a very unique, stylish package that really made a good first impression about the quality of this company.
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Jeroen Stapper
17:21 21 Jun 19
I like the fact they care about cannabis. I can see that in their packaging and the info they provide on the site. Good shop, will order from them again.
Robert Nijhout
Robert Nijhout
18:48 05 Jul 19

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