Cannabis can help with depression through a number of cannabinoids and terpenes that work together through the Entourage Effect. One of the main ways cannabis combats depression is due to the positive effect CBD has on the production of serotonin by acting on the 5HT1A receptors in the brain. This effect is amplified by terpenes such as limonene and caryophyllene. 

THC, on its own, acts on the CB1/CB2 receptors, creating a buffer against depression due to its psychoactive effect (in low to medium doses). Together, THC and CBD can alleviate the major symptoms of depression like; insomnia, fatigue, loss of appetite and chronic pain.

According to the World Health Organisation (WHO more than 300 million people across the world experience depression. If you’re experiencing anxiety, low self-esteem, chronic stress and or a lack of appetite and sleep, there is a distinct possibility that you could be one of those millions who is currently fighting depression.

But have you considered the possibility that medical marijuana could actually be used to treat depression?

The common symptoms of depression include continuous low mood or sadness, feeling hopeless and helpless, having low self-esteem and or feelings of anxiety. While pharmaceutical drugs remain the most common treatments for depression, many more people are now considering several alternatives like medical cannabis. 

Indeed, in recent years, a growing body of scientific research has come to light, indicating strongly that medical marijuana has serious potential in helping to reduce the symptoms related to depression.

Research Highlights the Efficacy of Cannabis as a Treatment for Depression

The fascinating world of cannabis health continues to arouse the curiosity of scientists around the globe. As such, it was only natural for them to study the potential effects and medical benefits that medical cannabis could have when used as a treatment for the depression crisis that seems to be engulfing so much of our planet.

In September of 2019, a study published in the Journal of Affective Disorders, suggested that inhaling cannabis can significantly reduce short-term levels of depression. Of those taking part in the analysis, 89.3% experienced a significant reduction in feelings of depression. 

The analysis also revealed that cannabis was effective in reducing anxiety (over the short-term) and stress. Another study conducted in 2014 was carried out to understand the effects of CBD, one of the dominant cannabinoids in the cannabis plant. The analysis revealed that CBD interacted with the serotonin receptors in our brain, which, in turn, helped to lower anxiety and depression levels. 

As the level of research on cannabis increases, It is now thought that it could potentially help with depression relief through a number of cannabinoids and terpenes contained within the plant that synergise through the Entourage Effect. 

The Best Marijuana Strains for Depression 

There are many strains that may help in curbing depression symptoms due to the chemical balance of cannabinoids and cannabis terpenes displayed in the cannabis plant. 

With research and user testimony indicating that medical marijuana has the potential to treat depression, many people have started using different marijuana strains as an alternative treatment for the condition. For beginners, it can be a bit daunting trying to understand the differences between indica strains, sativa strains and CBD strains. 

Indeed, understanding the type of cannabis strains best suited to your needs is vital when using medical marijuana so, to help you on your way, we have compiled a list of some of the best strains for treating depression.

Pineapple Express

An increasingly popular choice and one of the best strains for treating depression is the world-famous hybrid Pineapple Express. This wonderfully uplifting strain boasts the combination of effectiveness and flavour or its parents, Trainwreck and Hawaiian.

The heavy-hitting combination of Trainwreck and Hawaiian produces a wonderful sativadominant hybrid with a THC ratio somewhere between 17-20% with low CBD readings of less than 1%.

With a terpene profile that contains caryophyllene, limonene and myrcene, this hugely popular cannabis cup winner can help to energize the body, and improve productivity, making it an excellent strain to treat depression.

Blue Dream

A sativadominant hybrid, with high levels of THC, Blue Dream is thought to be one of the best strains for relaxing both mind and body which also makes it one of the best cannabis strains for depression. 

With a high THC ratio (approaching 20%) Blue Dream is one of the more potent strains and thought to be particularly effective in the treatment of stress and depression. Blue Dream ́s terpene profile shows high levels of limonene, pinene, and myrcene that may help to control mood disorders.

A cross of Blueberry with Haze, Blue Dream is a sativa strain that achieves full-body relaxation with some subtle cerebral stimulation. With a sweet berry aroma similar to that of its Blueberry parent, Blue Dream can help to treat depression without any heavy sedative effects. As such, Blue Dream is a popular daytime medicine for those looking for a little depression relief. 

Sour Diesel

Commonly known as Sour D, this fantastic hybrid strain has the potential to aid several stress disorders, including physical pain, and, depression and anxiety.

Another sativa strain, this time a  sativadominant hybrid that is said to have descended from Chemdog 91 and Super Skunk, Sour Diesel is rich in terpenes caryophyllene, myrcene, and limonene that lend itself to this strains peppery, citrus-like aroma and taste. This fast-acting behemoth can produce energising cerebral effects that have made Sour Diesel a legendary strain amongst cannabis enthusiasts and medical patients looking to treat mood disorders.

With a high THC ratio between 16 and 20%,  Sour Diesel has the potential to lift your mood and energy levels, making it a great cannabis strain that could provide a strong antidepressant effect for those suffering from depression. 

Jack Herer

A descendant of Shiva Skunk and Northern Lights #5. Jack Herer is a wildly popular hybrid strain that is famed for its uplifting qualities and antidepressant effect that is said to induce both happiness and creativity.

This type of strain, a sativadominant hybrid, is favoured by many for their stress-relieving effects as well as their balanced blend of sativa and indica effects.

Jack Herer’s THC ratio usually sits around 15 to 20%, with its dominant terpenes terpinolene, limonene and pinene thought to be particularly useful in boosting mood and focus. With a rich, piney, woody aroma, Jack Herer is a smooth yet potent strain and amongst seasoned marijuana users, remains one of the best strains for treating depression and reducing anxiety. 

Other strains worthy of a mention include OG Kush, Super Silver Haze and any of the classic Cookies strains which can all prove to be potentially effective in reducing the symptoms of depression and anxiety.

Indeed, the potential benefits of cannabis on the mind and body seem to be endless so If you ́re one of the millions suffering from depression and you’re interested in growing your own cannabis to help treat depression, please visit our growing community for more information on our huge selection of award-winning and popular strains for depression relief.

We have a vast range of seeds including sativa and indica strains, CBD strains, CBD oils and much more to choose from including popular strains like Mango Kush, Girl Scout Cookies and Northern lights.

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    Dance World CBD

    • Dancehall 20
    • Juanita La Lagrimosa

    Feminized | Medicinal

    Dance World CBD by Royal Queen Seeds is a 75% sativa hybrid with strong indica traits. This is a strain with great medical properties, attributable to the very high CBD content and equally balanced THC levels. The overall effect is a mix of physical and mental sensation of total wellbeing.

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    Euphoria CBD

    • Royal Medic
    • Shark Shock

    Feminized | Medicinal

    Euphoria CDB is an 80% indica hybrid that’s rewarding to both grow and consume, and although low in THC, its high CBD content (almost 1:1) compensates for loss of psychoactivity.

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    Royal Highness

    • Dance Hall
    • Juanita La Lagrimosa

    Feminized | Medicinal

    Royal Highness CBD is a gem of the Royal Queen Seeds’ family. 60% sativa-dominant, 3rd winner of Best CBD Flower at Colorado Cannabis Cup 2016. This strain has a high CBD level, pleasant aroma, structural characteristics typical to an indica, and a super-stimulating sativa high. Kneel before Her Majesty the Queen.

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    Strawberry Glue

    • Strawbanana
    • Goji Glue

    Feminized | Medicinal

    For enthusiasts of the Glue strains that have soared in popularity recently; Strawberry Glue is a potent, large yielding, exceptionally flavorsome hybrid reflecting the best traits of both parents. This strain is something special for cannasseurs.

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    Jock Horror

    • Mexican Haze
    • Northern Lights
    • Skunk #1

    | Medicinal

    There is no school like the old school…and Jock Horror is the headmaster. With an unbelievable potency compared to modern day strains, 24% THC may be a bit more shock horror than Jock Horror for newbies. More experienced smokers with an affinity for cerebral kicks, proceed if you dare!

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    Nebula CBD

    • Nebula

    Feminized | Medicinal

    Nirvana Seeds kept medical patients in mind when developing this strain. Nebula CBD is a sativa-dominant strain that has equal parts THC and CBD, a feat in and of itself. With Nebula CBD, you’ll be able to relax without any unwanted anxious side effects.

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    CBD Crack

    • Green Crack
    • Ruderalis

    Autoflowering | Medicinal

    As the name suggests, CBD Crack is both high in the therapeutic cannabinoid CBD and has a wonderful fruity flavor that will keep you coming back for more. Great for in the daytimes, with low THC.

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    Cannatonic

    Feminized, Regular | Medicinal

    For those of you looking for a medicinal cannabis strain, Cannatonic by Resin Seeds could be one of the most effective available on the market today. High in CBD and low in THC, Cannatonic is favoured by medicinal patients looking to reduce their symptoms with fewer of the psychotropic effects associated with high in THC strains.

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    Blackberry

    • Black Domina
    • Raspberry Cough

    | Medicinal

    A pleasurable and relaxing smoke, Blackberry is a relatively easy grow that yields a large amount of flowers. You’ll be kissing your worries goodbye in a cloud of fruity smoke after trying out this hybrid.

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    Skunk #11

    • Skunk #1

    Feminized | Medicinal

    With unique characteristics, Skunk #11 is an easy-to-grow strain that provides users a stunning combination of stone and high, perfect for indoor, outdoor, and greenhouse cultivation.

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    CBD Compassion

    • Nepalese

    Feminized | Medicinal

    A specially cultivated high CBD strain from Dutch Passion, CBD Compassion boasts a 1:1 CBD/THC ratio, averaging 8% for both cannabinoids. It is promising for medical users as it also has a good deal of CBC and CBG, providing a potentially rewarding ‘entourage effect’. Tasty too. 

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    CBD Kush

    • Kandy Kush

    Feminized | Medicinal

    CBD Kush has a mix of indica and sativa genetics that impresses with high yields and a satisfying flavor. Both recreational and medical users need not worry, as it has all of the healing properties sought, without the strong psychoactive effects.

    This product is currently out of stock and unavailable.

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    CBD Enriched Warlock

    • Cannatonic
    • G13 Haze
    • MK Ultra

    Feminized | Medicinal

    Serious Seeds crossed medical patients’ favorite, Warlock (indica dom) with the super high-CBD strain, Cannatonic. The resulting Limited Edition CBD Enriched Warlock is a turbocharged delight for your immune system. 4+% CBD and little to no psychoactive effects.

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    CBD Chronic

    • Chronic
    • Remedy

    Feminized | Medicinal

    CBD Chronic, Chronic (hybrid) x Remedy (indica), was purposefully bred by Serious Seeds to get a high CBD level and be easy growing; a special medicinal strain perfect for new growers.

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    White Haze

    • Haze 1
    • Unkown

    | Medicinal

    White Haze, Sensi Seeds’ White Label interpretation of the famed and fabulous Haze strain, won first prize at the 2002 Cannabis Cup.

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To ensure this, we use plain 20x27 white bubble wrap envelopes without any visible labelling except for your adres and our return address.
Our company name will read as “Guru Trading BV”. No other company labels, receipts or any references to cannabis are included on the envelope.

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What our users say

This website was recommended to me, it was exactly what I was looking for. So much useful information, I could literally read for hours. This is now where I get my CBD oil and my purple punch seeds are growing nicely. They also have really unique and useful packaging for the seeds. Cool company!
siun mcfaden
siun mcfaden
19:01 19 Jun 19
Personalized customer service and updates to the status of the order. I would very much recommend Coffeeshop Guru. In addition, they carry specialized seeds for less that other shops. I am a very happy client.
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April Fregd
11:30 06 Jul 19
Informative website. Products are delivered with care. I am very satisfied with my new Amnesia Haze seeds. Let them grow, Guru go go go!
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Pieter Van Vliet
14:50 24 Jun 19
I'm impressed with the website and the variety of products they stock. My order arrived in a very unique, stylish package that really made a good first impression about the quality of this company.
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Jeroen Stapper
17:21 21 Jun 19
I like the fact they care about cannabis. I can see that in their packaging and the info they provide on the site. Good shop, will order from them again.
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Robert Nijhout
18:48 05 Jul 19

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